Amirali Aghazadeh

I am an Assistant Professor in the School of Electrical and Computer Engineering at the Georgia Institute of Technology. I serve as Program Faculty in the Ph.D. programs in Machine Learning, Bioinformatics, and Bioengineering, and am affiliated with IDEaS, IMS, SRI, and the Petit Institute for Bioengineering and Bioscience (IBB).

Prior to joining Georgia Tech, I was a postdoctoral researcher at Stanford and UC Berkeley, and earned my Ph.D. from Rice University.

I am broadly interested in machine learning and AI for scientific discovery, with a focus on developing scalable methods for learning, generation, interpretation, and reasoning in complex combinatorial design spaces. Recent interests are:

• Discrete generative and diffusion models
• Protein sequence–function modeling, representation learning, and design
• Mechanistic interpretability
• Agentic AI, safety, and biosecurity
• Computational methods for protein imaging: cryo-EM
• Automated discovery in chemistry and the origins of life

I pronounce my first name Ah-meer-ah-lee and my last name Ah-gah-zah-deh. If you find it easier call me

• Watch my talk on Mech Interp of pLMs: Adaptable Computing for Omics.
• Watch my talk on Agentic AI for Hypothesis Generation: ICLR Agentic AI Workshop.
• Watch my talk on Epistasis and Protein Fitness Modeling at the Broad Institute: Models, Inference, and Algorithms (MIA).